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Article

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.

Cell calcium - 1 Jul 2006

Dabertrand Fabrice, Morel Jean-Luc, Sorrentino Vincenzo, Mironneau Jean, Mironneau Chantal, Macrez Nathalie

Abstract excerpt

The ryanodine receptor subtype 3 (RYR3) is expressed ubiquitously but its physiological function varies from cell to cell. Here, we investigated the role of a dominant negative RYR3 isoform in Ca2+ signalling in native smooth muscle cells. We used intranuclear injection of antisense oligonucleotides to specifically inhibit endogenous RYR3 isoform expression. In mouse duodenum myocytes expressing RYR2 subtype and...

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Source

Identifiers

PMID: 16678258
DOI: 10.1016/j.ceca.2006.03.008

Genes

RYR3
RYR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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