Article
HLA associations in clozapine-induced agranulocytosis.
Blood - 1 Aug 1995
Yunis J J, Corzo D, Salazar M, Lieberman J A, Howard A, Yunis E J
Abstract excerpt
We previously reported preliminary results of association of clozapine-induced agranulocytosis (CA) with HLA-B38, DR4, DQ3 in five Ashkenazi Jewish patients and with HLA-DR2, DQ1 in four non-Jewish patients. In the present study, 31 additional patients with CA, 10 Ashkenazi Jewish, and 21 of non-Jewish ancestry, were studied. HLA alleles and haplotypes were compared among 52 patients (33 Ashkenazi Jewish, 19...
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