Article
HLA associations in clozapine-induced agranulocytosis.
Blood - 1 Aug 1995
Yunis J J, Corzo D, Salazar M, Lieberman J A, Howard A, Yunis E J
Abstract excerpt
We previously reported preliminary results of association of clozapine-induced agranulocytosis (CA) with HLA-B38, DR4, DQ3 in five Ashkenazi Jewish patients and with HLA-DR2, DQ1 in four non-Jewish patients. In the present study, 31 additional patients with CA, 10 Ashkenazi Jewish, and 21 of non-...
Topics
- Adult
- Agranulocytosis
- Alleles
- Base Sequence
- Clozapine
- DNA Primers
- Female
- Gene Frequency
- Genes, MHC Class I
- Genes, MHC Class II
- HLA-B Antigens
- HLA-B38 Antigen
- HLA-DQ Antigens