Mapping of the amino acids in the cytoplasmic loop connecting helices C and D in rhodopsin. Chemical reactivity in the dark state following single cysteine replacements.

doi:10.1021/bi00027a032

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Article

Mapping of the amino acids in the cytoplasmic loop connecting helices C and D in rhodopsin. Chemical reactivity in the dark state following single cysteine replacements.

Biochemistry - 11 Jul 1995

Ridge K D, Zhang C, Khorana H G

Abstract excerpt

The cytoplasmic loop connecting helices C and D in rhodopsin is a part of the region involved in protein-protein interactions during signal transduction. To probe the structure of the CD loop, we have replaced, one at a time, the amino acids 136-150 by cysteine residues. The cysteine substitution...

Topics

Amino Acid Sequence
Animals
Cattle
Cysteine
Cytoplasm
Darkness
Ethylmaleimide
GTP-Binding Proteins
Molecular Sequence Data
Mutation
Protein Structure, Secondary
Rhodopsin

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