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Article

Degradation of channelopsin-2 in the absence of retinal and degradation resistance in certain mutants.

Biological chemistry - 1 Feb 2013

Ullrich Sybille, Gueta Ronnie, Nagel Georg

Abstract excerpt

Channelrhodopsin-2 is a light-gated cation channel from the green alga Chlamydomonas reinhardtii. It is functional in animal cells and therefore widely used for light-activated depolarization, especially in neurons. To achieve a fully functional protein, the chromophore all-trans-retinal is needed. It has not been investigated whether or not the apoprotein is stable without its cofactor until now. Here we show...

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Identifiers

PMID: 23134970
DOI: 10.1515/hsz-2012-0256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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