Article
Shared phenotypic expression of osteoblasts and chondrocytes in fracture callus.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Apr 1995
Hughes S S, Hicks D G, O'Keefe R J, Hurwitz S R, Crabb I D, Krasinskas A M, Loveys L, Puzas J E, Rosier R N
Abstract excerpt
Endochondral ossification in fracture healing of rats at 4, 8, 11, 14, and 21 days was analyzed using immunological and molecular probes for markers of the chondrocyte and osteoblast phenotype. These markers were osteocalcin, type I and type II collagen, including the probes homologous to the alt...
Topics
- Animals
- Bony Callus
- Calcification, Physiologic
- Cartilage
- Cell Differentiation
- Collagen
- DNA, Complementary
- Disease Models, Animal
- Female
- Fracture Healing
- Fractures, Bone
- Immunohistochemistry
- In Situ Hybridization
- Oligonucleotide Probes