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Article

Subchondral bone osteoblasts induce phenotypic changes in human osteoarthritic chondrocytes.

Osteoarthritis and cartilage - 1 Nov 2005

Sanchez C, Deberg M A, Piccardi N, Msika P, Reginster J-Y L, Henrotin Y E

Abstract excerpt

OBJECTIVE: To determine the influence of osteoarthritic (OA) phenotype of subchondral osteoblasts on the phenotype of human chondrocytes. METHODS: Human chondrocytes were isolated from OA cartilage and cultured in alginate beads for 4 or 10 days in the absence or in the presence of osteoblasts in monolayer. The osteoblasts were either isolated from non-sclerotic (N) or sclerotic (SC) zones of human subchondral...

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PMID: 16168681
DOI: 10.1016/j.joca.2005.07.012

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SOX9
PTH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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