Article
Site-specific differences in osteoblast phenotype, mechanical loading response and estrogen receptor-related gene expression.
Molecular and cellular endocrinology - 5 Dec 2018
Gharibi Borzo, Ghuman Mandeep S, Cama Giuseppe, Rawlinson Simon C F, Grigoriadis Agamemnon E, Hughes Francis J
Abstract excerpt
The osteoporosis-resistant nature of skull bones implies inherent differences exist between their cellular responses and those of other osteoporosis-susceptible skeletal sites. Phenotypic differences in calvarial and femoral osteoblastic responses to induction of osteogenesis, mechanical loading, estrogen, growth factor and cytokine stimulation were investigated. Primary rat calvarial and femoral adult male...
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