Article
A single mutation within the V3 envelope neutralization domain of feline immunodeficiency virus determines its tropism for CRFK cells.
Journal of virology - 1 Aug 1995
Verschoor E J, Boven L A, Blaak H, van Vliet A L, Horzinek M C, de Ronde A
Abstract excerpt
Feline immunodeficiency virus (FIV) isolates differ in the ability to replicate in Crandell feline kidney (CRFK) cells. The difference in tropism between two variants of the Dutch isolate FIV-UT113 was studied by using molecular clones which contained the envelope genes of the variants in a backg...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cats
- Cell Line
- Cloning, Molecular
- DNA Primers
- Deoxyribonuclease HindIII
- Immunodeficiency Virus, Feline
- Molecular Sequence Data
- Mutation
- Neutralization Tests