The role of environmental carcinogens, viruses and genetic predisposition in the pathogenesis of mesothelioma.

Abstract excerpt

Mesothelioma is one of the most aggressive human cancers and kills approximately 2500 people per year in the US. This cancer was almost unknown until the second half of the 20th century, and its rapid increase has been linked to the widespread use of asbestos. In spite of an enormous research effort, the mechanisms of asbestos carcinogenicity have remained an enigma. Why only a fraction of individuals exposed to...

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