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Article

Restriction fragment length polymorphism analysis of HLA-DR- and DQ-linked alleles in multiple sclerosis in Spain.

Journal of neuroimmunology - 1 Dec 1992

Clerici N, Fernández M

Abstract excerpt

HLA-DR allele subtypes in multiple sclerosis (MS) individuals in Spain were determined by restriction fragment length polymorphism (RFLP) analysis. The well-established association of DRw15, DQw6, Dw2 alleles and MS susceptibility was confirmed. The strength of its association, however, was relatively weak in our MS population and no involvement with any other DR allele was observed. DQw6 increase correlated with...

Topics

Alleles
Genotype
HLA-DQ Antigens
HLA-DR Antigens
Humans
Multiple Sclerosis
Polymorphism, Restriction Fragment Length
Spain

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1361490
DOI: 10.1016/0165-5728(92)90076-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1361490-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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