Article
Analysis of HLA DP, DQ, and DR alleles in adult Italian rheumatoid arthritis patients.
Human immunology - 1 Jun 1992
Angelini G, Morozzi G, Delfino L, Pera C, Falco M, Marcolongo R, Giannelli S, Ratti G, Ricci S, Fanetti G
Abstract excerpt
We analyzed the distribution of DRB1, DQA1, DQB1, and DPB1 allelic variants in 48 rheumatoid arthritis (RA) patients, compared with 109 Italian random controls, using PCR amplification and hybridization with specific oligonucleotides. We confirm the previously reported increase of DR4 specificity...
Topics
- Adult
- Aged
- Alleles
- Amino Acid Sequence
- Arthritis, Rheumatoid
- Autoimmune Diseases
- Base Sequence
- Disease Susceptibility
- Female
- Gene Frequency
- Genes, MHC Class II
- Genetic Predisposition to Disease
