Article
Long bone geometry and strength in adult BMP-5 deficient mice.
Bone - 1 Apr 1995
Mikić B, van der Meulen M C, Kingsley D M, Carter D R
Abstract excerpt
Bone morphogenetic proteins (BMPs) play a critical role in early skeletal development. BMPs are also potential mediators of bone response to mechanical loading, but their role in later stages of bone growth and adaptation has yet to be studied. We characterized the postcranial skeletal defects in mature mice with BMP deficiency by measuring hind-limb muscle mass and long bone geometric, material, and torsional...
Topics
- Analysis of Variance
- Animals
- Biomechanical Phenomena
- Bone Density
- Bone Morphogenetic Protein 5
- Bone Morphogenetic Proteins
- Bone and Bones
- Female
- Femur
- Genotype
- Growth Substances
- Hindlimb
