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Article

Three novel variants in the coagulation factor V gene associated with deep venous thrombosis in Chilean patients with Amerindian ethnic background.

Clinica chimica acta; international journal of clinical chemistry - 15 Apr 2015

Guzmán Neftalí, Larama Giovanni, Ávila Andrés, Salazar Luis A

Abstract excerpt

BACKGROUND: The activated protein C (APC) resistance is the most common prothrombotic defect in thrombosis patients, mainly related with alterations in the F5 gene. In this work, we evaluated the presence of variants in the FV gene in Amerindian patients with deep venous thrombosis and APC resistance. METHODS: A total of 87 patients with deep venous thrombosis (DVT) confirmed by Doppler ultrasonography, and...

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Identifiers

PMID: 25668227
DOI: 10.1016/j.cca.2015.02.002

Genes

APC

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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