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Article

Epidemiology of Factor V Leiden: Clinical Implications

1 Aug 1998

Abstract excerpt

Inherited resistance to activated protein C (APC) has been recently recognized as a novel cause underlying venous thrombophilia. In most cases APC resistance is due to a single point mutation in the factor V gene leading to a replacement of Arg506 with Gln (factor V Leiden). Factor V Leiden allele is present in about 5% of the Caucasian individuals (Europeans, Jews, Israeli Arabs, and Indians) and is virtually...

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Share to Blood Coagulation and Thrombosis Mechanisms
Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
Share to Venous Thromboembolism Diagnosis and Management

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Identifiers

PMID: 9763354
DOI: 10.1055/s-2007-996025

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