Article
Binding between wild-type p53 and hsp72 accumulated after UV and gamma-ray irradiation.
Cancer letters - 8 Jun 1995
Matsumoto H, Wang X, Ohnishi T
Abstract excerpt
We have investigated the increased levels of p53 and hsp72 after UV or gamma-ray irradiation and the association of these using two human glioblastoma cell lines. Human glioblastoma cell line A-172 exhibited no mutations in the p53 gene, whereas cell line T98G had a mutation in exon 7 of the p53...
Topics
- Blotting, Western
- Gamma Rays
- Genes, p53
- Glioblastoma
- Heat-Shock Proteins
- Humans
- Mutation
- Neoplasm Proteins
- Protein Binding
- Tumor Cells, Cultured
- Tumor Suppressor Protein p53
- Ultraviolet Rays
