Structure-function analysis of the histidine permease and comparison with cystic fibrosis mutations.

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Article

Structure-function analysis of the histidine permease and comparison with cystic fibrosis mutations.

The Journal of biological chemistry - 5 Oct 1991

Shyamala V, Baichwal V, Beall E, Ames G F

Abstract excerpt

Traffic ATPases constitute a superfamily of transporters that include prokaryotic permeases and medically important eukaryotic proteins, such as the multidrug resistance P-glycoprotein and the cystic fibrosis gene product. We present a structure-function analysis of a member of this superfamily,...

Topics

ATP-Binding Cassette Transporters
Amino Acid Sequence
Amino Acid Transport Systems, Basic
Bacterial Proteins
Cells, Cultured
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Genes, Suppressor
Humans
Membrane Proteins
Membrane Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutagenesis, Site-Directed

Mutation

Sequence Alignment

Structure-Activity Relationship

Suppression, Genetic

Source

Open in PubMed

Identifiers

PMID: 1717452

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1717452-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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