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Article

RET-deficient mice: an animal model for Hirschsprung's disease and renal agenesis.

Journal of internal medicine - 1 Oct 1995

Schuchardt A, D'Agati V, Larsson-Blomberg L, Costantini F, Pachnis V

Abstract excerpt

Receptor tyrosine kinases play a critical role in transducing signals involved in cell growth and differentiation. The c-ret proto-oncogene is a member of the receptor tyrosine kinase gene superfamily originally identified by its transforming ability. Somatic mutations of c-ret are responsible for a large proportion of thyroid papillary carcinomas, while germ-line mutations are responsible for multiple endocrine...

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Source

Identifiers

PMID: 7595168
DOI: 10.1111/j.1365-2796.1995.tb01206.x

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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RET-deficient mice: an animal model for Hirschsprung's disease and renal agenesis.PMID 7595168Read ↗

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Current concepts in RET-related genetics, signaling and therapeutics.Semantic proximity Read ↗

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