Isolation and characterization of a putative liver progenitor population after treatment of fetal rat hepatocytes with TGF-beta.

doi:10.1002/jcp.21370

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Isolation and characterization of a putative liver progenitor population after treatment of fetal rat hepatocytes with TGF-beta.

Journal of cellular physiology - 1 Jun 2008

del Castillo Gaelle, Alvarez-Barrientos Alberto, Carmona-Cuenca Irene, Fernández Margarita, Sánchez Aránzazu, Fabregat Isabel

Abstract excerpt

The "in vitro" establishment of a physiological model of bipotential liver progenitors would be useful for analyzing the molecular mechanisms involved in regulating growth and differentiation, as well as studying their potential role/s in liver physiology and pathology. The transforming growth factor-beta (TGF-beta) induces de-differentiation of fetal rat hepatocytes (FH), concomitant with changes in morphology....

Topics

Albumins
Animals
Apoptosis
Cell Differentiation
Cell Lineage
Cell Separation
Cell Survival
Cells, Cultured
Dimethyl Sulfoxide
Fetus
Hepatocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Liver

Phenotype

Rats

Rats, Wistar

Reactive Oxygen Species

Stem Cells

Source

Open in PubMed

Identifiers

PMID: 18286537
DOI: 10.1002/jcp.21370

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Isolation and characterization of a putative liver progenitor population after treatment of fetal rat hepatocytes with TGF-beta.PMID 18286537Read ↗

The transforming growth factor-beta (TGF-β) mediates acquisition of a mesenchymal stem cell-like phenotype in human liver cells.Semantic proximity Read ↗

Hepato-biliary profile of potential candidate liver progenitor cells from healthy rat liver.Semantic proximity Read ↗

Isolation and characterization of a murine resident liver stem cell.Semantic proximity Read ↗

Population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF and TGF alpha in a chemically defined (HGM) medium.Semantic proximity Read ↗

TGF-β serves as a critical signaling determinant of liver progenitor cell fate and functionSemantic proximity Read ↗

Implication of hepatic stem cells in functional liver repopulationSemantic proximity Read ↗

Differentiation of neonatal rat epithelial cells from biliary origin into immature hepatic cells by sequential exposure to hepatogenic cytokines and growth factors reflecting liver development.Semantic proximity Read ↗

Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cellsSemantic proximity Read ↗

Growth and differentiation of colony-forming human hepatocytes in vitro.Semantic proximity Read ↗

Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cellsSemantic proximity Read ↗

BMP9 Promotes an Epithelial Phenotype and a Hepatocyte-like Gene Expression Profile in Adult Hepatic Progenitor Cells.Semantic proximity Read ↗

Identification and characterization of mesenchymal-epithelial progenitor-like cells in normal and injured rat liver.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.