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Article

Hepatocyte growth factor activates the AP-1 complex: a comparison between normal and transformed rat hepatocytes.

Journal of hepatology - 1 May 1999

Rahmani M, Nadori F, Durand-Schneider A M, Lardeux B, Bernuau D

Abstract excerpt

BACKGROUND/AIMS: Stimulation of activator protein-1 (AP-1), a Fos/Jun complex, is a key event in the cell response to growth factors. We have investigated whether hepatocyte growth factor (HGF) induces differential AP-1 responses in normal and transformed rat hepatocytes, the 7777 cells. METHODS: Primocultures of isolated hepatocytes or 7777 cells were stimulated with HGF. Gene expression was evaluated by...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10365821
DOI: 10.1016/s0168-8278(99)80148-2

Genes

HGF
CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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