Article
Genetic interaction with vps8-200 allows partial suppression of the vestigial vacuole phenotype caused by a pep5 mutation in Saccharomyces cerevisiae.
Genetics - 1 Jan 1998
Woolford C A, Bounoutas G S, Frew S E, Jones E W
Abstract excerpt
pep5 mutants of Saccharomyces cerevisiae accumulate inactive precursors to the vacuolar hydrolases. In addition, they show a vestigial vacuole morphology and a sensitivity to growth on media containing excess divalent cations. This pleiotropic phenotype observed for pep5::TRP1 mutants is partiall...
Topics
- Alleles
- Carrier Proteins
- Epistasis, Genetic
- Fungal Proteins
- Genes, Fungal
- Genes, Suppressor
- Hydrolases
- Microscopy, Electron
- Mutation
- Phenotype
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Suppression, Genetic
- Vacuoles
- Vesicular Transport Proteins