Article
Genetic and phenotypic overlap between autophagy and the cytoplasm to vacuole protein targeting pathway.
The Journal of biological chemistry - 26 Jul 1996
Harding T M, Hefner-Gravink A, Thumm M, Klionsky D J
Abstract excerpt
We have explored the phenotypic and genetic overlap between autophagocytosis and cytoplasm to vacuole targeting in the yeast Saccharomyces cerevisiae. Complementation analysis was performed with mutants in each of these groups (aut and cvt, respectively), and three complementation groups were found to overlap. Also, most of the unique aut mutants accumulated precursor aminopeptidase I in the cytoplasm, while...
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