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Article

Dynein and Star interact in EGFR signaling and ligand trafficking.

Journal of cell science - 15 Aug 2008

Iyadurai Stanley J P, Robinson John T, Ma Lingzhi, He Yungui, Mische Sarah, Li Min-Gang, Brown William, Guichard Annabel, Bier Ethan, Hays Thomas S

Abstract excerpt

Intracellular transport and processing of ligands is critical to the activation of signal transduction pathways that guide development. Star is an essential gene in Drosophila that has been implicated in the trafficking of ligands for epidermal growth factor (EGF) receptor signaling. The role of cytoplasmic motors in the endocytic and secretory pathways is well known, but the specific requirement of motors in EGF...

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Source

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Identifiers

PMID: 18653542
DOI: 10.1242/jcs.027144
PMCID: PMC2633900

Genes

EGF
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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