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Article

Modular organization of T4 DNA polymerase. Evidence from phylogenetics.

The Journal of biological chemistry - 3 Nov 1995

Wang C C, Yeh L S, Karam J D

Abstract excerpt

We describe the use of a phylogenetic approach to analyze the modular organization of the single-chained (898 amino acids) and multifunctional DNA polymerase of phage T4. We have identified, cloned in expression vectors, and sequenced the DNA polymerase gene (gene 43) of phage RB69, a distant relative of T4. The deduced primary structure of the RB69 protein (RB69 gp43) differs from that of T4 gp43 in discrete...

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PMID: 7592876
DOI: 10.1074/jbc.270.44.26558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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