Article
The helicase domain of phage P4 alpha protein overlaps the specific DNA binding domain.
Journal of bacteriology - 1 Jul 1997
Ziegelin G, Calendar R, Lurz R, Lanka E
Abstract excerpt
Replication initiation depends on origin recognition, helicase, and primase activities. In phage P4, a second DNA region, the cis replication region (crr), is also required for replication initiation. The multifunctional alpha protein of phage P4, which is essential for DNA replication, combines the three aforementioned activities on a single polypeptide chain. Protein domains responsible for the activities were...
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