Article
BvgAS is sufficient for activation of the Bordetella pertussis ptx locus in Escherichia coli.
Journal of bacteriology - 1 Nov 1995
Uhl M A, Miller J F
Abstract excerpt
BvgA and BvgS, which regulate virulence gene expression in Bordetella pertussis, are members of the two-component signal transduction family. The effects of growth conditions on the ability of BvgAS to activate transcription of fhaB (encoding filamentous hemagglutinin) and ptxA (encoding the S1 subunit of pertussis toxin) were assessed in Escherichia coli by using chromosomal fhaB-lacZYA and ptxA-lacZYA fusions....
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