Article
Mutations in the bvgA gene of Bordetella pertussis that differentially affect regulation of virulence determinants.
Journal of bacteriology - 1 Sept 1994
Stibitz S
Abstract excerpt
By using chemical mutagenesis and genetic mapping, a search was undertaken for previously undescribed genes which may be involved in different regulatory mechanisms governing different virulence factors of Bordetella pertussis. Previous studies have shown that the fha locus encoding filamentous hemagglutinin is regulated directly by the bvgAS two component system, while regulation of ptx encoding pertussis toxin...
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