Article
Specific genetic changes of diagnostic importance in chromophobe renal cell carcinomas.
Laboratory investigation; a journal of technical methods and pathology - 1 Feb 1997
Bugert P, Gaul C, Weber K, Herbers J, Akhtar M, Ljungberg B, Kovacs G
Abstract excerpt
The histologic diagnosis of chromophobe renal cell carcinomas is often uncertain because of phenotype overlap among different types of kidney cancers. Recently, in a novel genetic classification of renal cell tumors, a combination of monosomies of chromosomes 1, 2, 3, 6, 10, 13, 17, and 21 have been suggested to have a diagnostic value for this unique type of tumor. Therefore, we have analyzed fresh and...
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