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Article

Expression of the cyclin-dependent kinase inhibitors p16INK4, p15INK4B and p21WAF1/CIP1 in human breast cancer.

International journal of cancer - 15 Nov 1995

Musgrove E A, Lilischkis R, Cornish A L, Lee C S, Setlur V, Seshadri R, Sutherland R L

Abstract excerpt

Aberrant cyclin expression has been implicated in oncogenesis in a number of human cancers. Since altered function of regulators of cyclin-dependent kinase (CDK) activity other than cyclins, in particular CDK inhibitors, might play a similar role in oncogenesis, we examined the expression and regulation of the CDK inhibitors p16INK4, p15INK4B and p21WAF1/CIP1 in human breast cancer cell lines. Both the INK4 and...

Topics

Base Sequence
Breast
Breast Neoplasms
Carrier Proteins
Cell Cycle Proteins
Cyclin-Dependent Kinase Inhibitor p15
Cyclin-Dependent Kinase Inhibitor p16
Cyclin-Dependent Kinase Inhibitor p21
Cyclin-Dependent Kinases
Cyclins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Enzyme Inhibitors

Female

Gene Deletion

Gene Expression

Humans

Molecular Sequence Data

Mutation

RNA, Messenger

Source

Identifiers

PMID: 7591270
DOI: 10.1002/ijc.2910630420

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7591270-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Expression of the cyclin-dependent kinase inhibitors p16INK4, p15INK4B and p21WAF1/CIP1 in human breast cancer.PMID 7591270Read ↗

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