Article
Variable sequences in a mosaic-like domain of meningococcal tbp2 encode immunoreactive epitopes.
FEMS microbiology letters - 15 Oct 1995
Rokbi B, Maitre-Wilmotte G, Mazarin V, Fourrichon L, Lissolo L, Quentin-Millet M J
Abstract excerpt
Transferrin-binding proteins from Neisseria meningitidis vary among different isolates. We have identified and studied a hypervariable region adjacent to the carboxyl-end of the transferrin-binding domain of the Tbp2 molecule. The tbp2 genes from six strains of N. meningitidis were cloned and seq...
Topics
- Antigens, Bacterial
- Bacterial Outer Membrane Proteins
- Base Sequence
- Carrier Proteins
- Enzyme-Linked Immunosorbent Assay
- Epitope Mapping
- Epitopes
- Genetic Variation
- Iron-Binding Proteins
- Molecular Sequence Data
- Neisseria meningitidis
- Peptides
- Polymerase Chain Reaction
- Sequence Analysis, DNA
- Sequence Homology, Nucleic Acid
- Transferrin-Binding Proteins