Hexamethylmelamine is a potent inducer of deletions in male germ cells of Drosophila melanogaster.

doi:10.1093/carcin/16.11.2679

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Article

Hexamethylmelamine is a potent inducer of deletions in male germ cells of Drosophila melanogaster.

Carcinogenesis - 1 Nov 1995

Aguirrezabalaga I, Nivard M J, Comendador M A, Vogel E W

Abstract excerpt

Chemotherapy-related second tumors constitute a matter of concern in cancer treatment. Therefore, it is of great interest to elucidate the mechanisms by which cytostatic drugs exert their mutagenic and/or carcinogenic activity besides the anticancer effect and the possible relationship among them...

Topics

Altretamine
Animals
Antineoplastic Agents, Alkylating
Base Sequence
Drosophila melanogaster
Gene Deletion
Male
Molecular Sequence Data
Mutagens
Mutation
Neoplasms, Second Primary
Spermatozoa

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