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Article

Lung cancer risk of the GSTM1 null genotype is enhanced in the presence of the GSTP1 mutated genotype in male Japanese smokers.

Cancer letters - 22 Mar 1999

Kihara M, Kihara M, Noda K

Abstract excerpt

The potential interaction of GSTM1 and GSTP1 genotypes in pulmonary carcinogenesis was assessed in 382 male Japanese lung cancer patients (127 squamous cell carcinoma, 78 small cell carcinoma, 177 adenocarcinoma) and 257 controls. In smokers (358 cases, 184 controls) the GSTM1 null genotype was more distributed in individuals with at least one GSTP1 mutant allele compared to those without, in lung cancer patients...

Topics

Adenocarcinoma
Aged
Alleles
Carcinoma, Small Cell
Carcinoma, Squamous Cell
Genotype
Glutathione Transferase
Humans
Lung Neoplasms
Male
Middle Aged
Smoking

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10376794
DOI: 10.1016/s0304-3835(98)00337-1

Genes

GSTM1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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