Article
Genetic analysis of glutathione peroxidase in oxidative stress response of Saccharomyces cerevisiae.
The Journal of biological chemistry - 17 Sept 1999
Inoue Y, Matsuda T, Sugiyama K, Izawa S, Kimura A
Abstract excerpt
Three glutathione peroxidase homologs (YKL026C, YBR244W, and YIR037W/HYR1) were found in the Saccharomyces Genome Database. We named them GPX1, GPX2, and GPX3, respectively, and we investigated the function of each gene product. The gpx3Delta mutant was hypersensitive to peroxides, whereas null mutants of the GPX1 and GPX2 did not show any obvious phenotypes. Glutathione peroxidase activity decreased...
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