Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isogenic radiation resistant cell lines: Development and validation strategies

18 Dec 2013

Abstract excerpt

PURPOSE: The comparison of cell lines with differing radiosensitivities and their molecular response to radiation exposure has been used in a number of human cancer models to study the molecular response to radiation. This review proposes to analyze and compare the protocols used by investigators for the development and validation of these isogenic models of radioresistance. CONCLUSION: There is large variability...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinogens and Genotoxicity Assessment
Share to Effects of Radiation Exposure
Share to Heat shock proteins research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24350914
DOI: 10.3109/09553002.2014.873557

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Isogenic radiation resistant cell lines: Development and validation strategiesPMID 24350914Read ↗

Development and characterization of an isogenic cell line with a radioresistant phenotype.Semantic proximity Read ↗

Mechanisms of different response to ionizing irradiation in isogenic head and neck cancer cell lines.Semantic proximity Read ↗

Differences in DNA Repair Capacity, Cell Death and Transcriptional Response after Irradiation between a Radiosensitive and a Radioresistant Cell LineSemantic proximity Read ↗

Factors and molecular mechanisms of radiation resistance in cancer cellsSemantic proximity Read ↗

Radioresistant human lung adenocarcinoma cells that survived multiple fractions of ionizing radiation are sensitive to HSP90 inhibition.Semantic proximity Read ↗

Alterations in DNA Repair Efficiency are Involved in the Radioresistance of Esophageal AdenocarcinomaSemantic proximity Read ↗

Reporting of methodologies used for clonogenic assays to determine radiosensitivitySemantic proximity Read ↗

Insights on the Radiation-Induced Adaptive Response at the Cellular Level and Its Implications in Cancer TherapySemantic proximity Read ↗

Characterization of Intrinsic Radiation Sensitivity in a Diverse Panel of Normal, Cancerous and CRISPR-Modified Cell LinesSemantic proximity Read ↗

Low-Dose Hypersensitivity and Increased Radioresistance in a Panel of Human Tumor Cell Lines with Different RadiosensitivitySemantic proximity Read ↗

Association between radiation-induced cell death and clinically relevant radioresistanceSemantic proximity Read ↗

Clinically relevant radioresistant rhabdomyosarcoma cell lines: functional, molecular and immune-related characterizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.