Article
Drug resistance patterns of human neuroblastoma cell lines derived from patients at different phases of therapy.
Cancer research - 1 Dec 1998
Keshelava N, Seeger R C, Groshen S, Reynolds C P
Abstract excerpt
To determine whether neuroblastomas acquire a sustained drug-resistant phenotype from exposure to chemotherapeutic agents given to patients in vivo, we studied neuroblastoma cell lines established at different points of therapy: six at diagnosis before therapy (DX), six at progressive disease during induction therapy (PD-Ind), and five at relapse after intensive chemoradiotherapy and bone marrow transplantation...
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