Article
[Allelic variations of DPB1, DQA1, DQB1 and DRB1 and rheumatoid arthritis: further genetic and statistical considerations].
Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna - 1 Jan 2000
Morozzi G, Galeazzi M, Delfino L, Pera C, Ferrara G B, Marcolongo R
Abstract excerpt
We used polymerase chain reaction amplification and hybridization with specific oligonucleotides to analyze the distribution of DPB1, DQA1, DQB1, and DRB1 allelic variants in 48 patients with rheumatoid arthritis (RA) and compared our results with those from 109 randomly chosen, healthy control subjects. Our work confirms a previously reported increase in DR4 specificity in RA: in particular, we found a...
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