[Systemic manifestations of rheumatoid arthritis: prognostic value of the HLA DRB1 0405 allele].

doi:10.1016/s0248-8663(05)80131-6

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Article

[Systemic manifestations of rheumatoid arthritis: prognostic value of the HLA DRB1 0405 allele].

La Revue de medecine interne - 1 Jan 1993

Flipo R M, Danze P M, Castelain V, Coquerel P, Duquesnoy B, Rousseaux J, Delcambre B

Abstract excerpt

The aim of the present study was to determine HLA DRB1* genotype by PCR-RFLP analysis in patients with rheumatoid arthritis (N = 122) associated with extra-articular manifestations (N = 24). A significant increased of DRB1* 0405 was found in RA patients with extra-cellular involvement (odd-ratio...

Topics

Alleles
Arthritis, Rheumatoid
HLA-DR Antigens
HLA-DRB1 Chains
Histocompatibility Antigens Class II
Humans
Prognosis

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