Article
Do the HLA-DQ and DP genes play a role in rheumatoid arthritis?
Joint bone spine - 1 Feb 2001
Perdriger A
Abstract excerpt
Whereas the DRB1 alleles have well-established associations with rheumatoid arthritis (RA), the DQ and DP alleles are of more controversial relevance to RA. Early studies of the DQB1 genes in RA determined the frequencies of the two DQB1*03 subtypes that are in linkage disequilibrium with DR4, DQB1*0301 (DQw7) and *0302 (DQw8). Their results are conflicting and difficult to interpret because molecular biology...
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