Article
Treatment of PC12 cells by nerve growth factor, dexamethasone, and forskolin. Effects on cell morphology and expression of neurotensin and tyrosine hydroxylase.
Molecular neurobiology - 1 Jan 2000
Caillaud T, Opstal W Y, Scarceriaux V, Billardon C, Rostene W
Abstract excerpt
Several lines of anatomical, neurochemical, electrophysiological, and behavioral evidence suggest the existence of physiological interactions between neurotensin (NT) and the brain dopaminergic systems. Thus, NT has been shown to exert a neuroleptic-like action and could be implicated in the pathogenesis and treatment of schizophrenia. It is thus of particular importance to develop in vitro cell culture systems...
Topics
- Animals
- Catecholamines
- Cell Differentiation
- Colforsin
- Dexamethasone
- Enzyme Induction
- Female
- Gene Expression Regulation, Neoplastic
- Neoplasm Proteins
- Nerve Growth Factors