Article
An in vitro model for the effects of estrogen on neurons employing estrogen receptor-transfected PC12 cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jun 1994
Lustig R H, Hua P, Yu W, Ahmad F J, Baas P W
Abstract excerpt
Estrogen alters neurite outgrowth, neuritic spine development, and synaptogenesis in estrogen-responsive areas of the rat brain. However, examination of the specific effects of estrogen on neurons in vivo has been difficult. An in vitro model for the effects of estrogen on neurons was developed,...
Topics
- Animals
- Antibodies
- Axons
- Cell Line
- Estrogens
- Gap Junctions
- Microscopy, Electron
- Nerve Growth Factors
- Neurites
- Neurons
- PC12 Cells
- Phenotype
- RNA, Messenger
- Rats
- Receptors, Estrogen
- Transfection