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Article

An in vitro model for the effects of estrogen on neurons employing estrogen receptor-transfected PC12 cells.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jun 1994

Lustig R H, Hua P, Yu W, Ahmad F J, Baas P W

Abstract excerpt

Estrogen alters neurite outgrowth, neuritic spine development, and synaptogenesis in estrogen-responsive areas of the rat brain. However, examination of the specific effects of estrogen on neurons in vivo has been difficult. An in vitro model for the effects of estrogen on neurons was developed, using the PC12 rat pheochromocytoma cell line. Wild-type cells (PC12-WT) were stably transfected either with an...

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Identifiers

PMID: 8207498
PMCID: PMC6576956

Genes

NGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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