Article
Evidence of HLA class II association with antibody response against the malaria vaccine SPF66 in a naturally exposed population.
The American journal of tropical medicine and hygiene - 1 Sept 1995
Beck H P, Felger I, Barker M, Bugawan T, Genton B, Alexander N, Jazwinska E, Erlich H, Alpers M
Abstract excerpt
The antibody response against the malaria vaccine SPf66 and against circumsporozoite (CS) protein has been tested in immune adults from a malaria endemic area in Papua New Guinea. All individuals were genotyped for the HLA class II DQB1 and DRB1 loci, and the humoral response was analyzed with re...
Topics
- Adolescent
- Adult
- Aged
- Animals
- Antibodies, Protozoan
- Base Sequence
- DNA Primers
- Genes, MHC Class II
- Genotype
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- HLA-DR Antigens
- HLA-DRB1 Chains
- Humans
- Malaria Vaccines