Article
Evidence of HLA class II association with antibody response against the malaria vaccine SPF66 in a naturally exposed population.
The American journal of tropical medicine and hygiene - 1 Sept 1995
Beck H P, Felger I, Barker M, Bugawan T, Genton B, Alexander N, Jazwinska E, Erlich H, Alpers M
Abstract excerpt
The antibody response against the malaria vaccine SPf66 and against circumsporozoite (CS) protein has been tested in immune adults from a malaria endemic area in Papua New Guinea. All individuals were genotyped for the HLA class II DQB1 and DRB1 loci, and the humoral response was analyzed with respect to the identified class II alleles. At each locus, only three alleles were frequent, namely DRB1*11, *15, and...
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