Article
Influence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax.
Acta tropica - 1 Feb 2012
Storti-Melo Luciane Moreno, da Costa Daniela Reis, Souza-Neiras Wanessa Christina, Cassiano Gustavo Capatti, Couto Vanja Suely Calvosa D'Almeida, Póvoa Marinete Marins, Soares Irene da Silva, de Carvalho Luzia Helena, Arevalo-Herrera Myrian, Herrera Sócrates, Rossit Andrea Regina Baptista, Cordeiro José Antonio, de Mattos Luiz Carlos, Machado Ricardo Luiz Dantas
Abstract excerpt
We evaluated the influence of allelic frequency of the human leukocyte antigen (HLA) -DRB1 on the acquisition of antibody response against malaria sporozoite and merozoite peptides in patients with Plasmodium vivax malaria acquired in endemic areas of Brazil. IgG antibodies were detected by enzyme-linked immunosorbent assay against four peptides of circumsporozoite protein (CSP) (amino, carboxyl, and VK210 and...
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