Article
Influence of HLA-DRB1 alleles on antibody responses to PfCP-2.9-immunized and naturally infected individuals.
Journal of clinical immunology - 1 Jul 2009
Zhang Qingfeng, Xue Xiangyang, Xu Xindong, Wang Cuiping, Chang Wenjun, Pan Weiqing
Abstract excerpt
INTRODUCTION: The Plasmodium falciparum chimeric protein, PfCP-2.9, which consists of apical membrane antigen (AMA)-1(III) and merozoite surface protein (MSP)1-19, is a promising asexual-stage malaria vaccine currently being evaluated in clinical trials. This study attempts to investigate the potential association between human leukocyte antigen (HLA)-DRB1 genotype and antibody response against PfCP-2.9 in...
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