Article
The influenza virus NS1 protein forms multimers in vitro and in vivo.
Virology - 1 Oct 1995
Nemeroff M E, Qian X Y, Krug R M
Abstract excerpt
The NS1 protein of the influenza A virus inhibits both the nuclear export of mRNA and pre-mRNA splicing. Two functional domains, an RNA-binding domain and an effector domain, have been identified in this protein. Here we demonstrate that the NS1 protein exists as a dimer in vitro both in the abse...
Topics
- Amino Acid Sequence
- Glutathione Transferase
- Molecular Sequence Data
- Mutation
- Orthomyxoviridae
- Protein Conformation
- RNA, Small Nuclear
- Recombinant Fusion Proteins
- Sequence Deletion
- Viral Nonstructural Proteins