Article
A mutant of pseudorabies virus with deletion of glycoprotein gIII gene prepared from a Japanese isolate: it fails to agglutinate mouse erythrocytes.
Veterinary microbiology - 1 Jul 1995
Yamada S, Imada T, Shimizu M, Miura Y
Abstract excerpt
A mutant with deletion of the glycoprotein gIII gene was produced from a Japanese isolate of pseudorabies virus (PrV) and characterized. Viral titers of the mutant propagated in PK-15 cells were always lower than those of the parental virus. The parental virus agglutinated BALB/c mouse erythrocytes, whereas the deletion mutant showed no hemagglutinating activity. Pigs inoculated with the parental virus produced...
Topics
- Animals
- Antibodies, Viral
- Gene Deletion
- Hemagglutination, Viral
- Herpesvirus 1, Suid
- Immunization
- Japan
- Mice
- Mice, Inbred BALB C
- Mutation
- Pseudorabies
