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Article

Estimation of the proportion of genetic cases in late-onset diseases: an application to Alzheimer's disease.

Statistics in medicine - 30 Jun 1995

Tzourio C, Maccario J, Alpérovitch A

Abstract excerpt

In diseases with a complex etiology including a genetic component, an important issue is to determine the proportion of cases really having inherited the disease. This is not easy in late-onset diseases where censoring might obscure the transmission pattern of the disease and give an apparently non-genetic distribution of the cases. We present a model that allows the estimation of the proportion of genetic cases...

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Identifiers

PMID: 7569493
DOI: 10.1002/sim.4780141208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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