Article
Is dementia of the Alzheimer type a purely genetic illness? A modelling approach.
Neuroepidemiology - 1 Jan 1991
Tzourio C, Alpérovitch A, Maccario J, Dartigues J F
Abstract excerpt
In some multiple-case families, dementia of the Alzheimer type (DAT) is very likely to be of a genetic origin. Nevertheless, most DAT cases are sporadic and a disease with a majority of sporadic cases is usually of environmental origin. Are there two different etiologies of DAT? And if so, what is the proportion of genetic cases? We describe a model designed to assess the genetic risk in DAT. Our basic hypotheses...
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