The accuracy of statistical estimates in genetic studies of aging can be significantly improved.

doi:10.1007/s10522-006-9072-4

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Article

The accuracy of statistical estimates in genetic studies of aging can be significantly improved.

Biogerontology - 1 Jun 2007

Yashin Anatoli I, Arbeev Konstantin G, Ukraintseva Svetlana V

Abstract excerpt

The sample size of the data used in genetic studies is often a factor limiting the accuracy of statistical estimates. In this paper we suggest a new approach to evaluation of genetic influence on risk of development of aging-related health disorders. The approach results in substantial improvement of the accuracy of statistical estimates without an increase in the size of the genetic sample. The approach is based...

Topics

Aging
Alleles
Data Interpretation, Statistical
Genotype
Humans
Longitudinal Studies
Models, Statistical
Sample Size

Source

Open in PubMed Open full text

Identifiers

PMID: 17160500
DOI: 10.1007/s10522-006-9072-4
PMCID: PMC1995667

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