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Article

Autosomal recessive causes likely in early-onset Alzheimer disease.

Archives of neurology - 1 Jan 2012

Wingo Thomas S, Lah James J, Levey Allan I, Cutler David J

Abstract excerpt

OBJECTIVES: To determine the genetic contribution to non-autosomal dominant early-onset Alzheimer disease (EOAD) (onset age ≤60 years) cases and identify the likely mechanism of inheritance in those cases. DESIGN: A liability threshold model of disease was used to estimate heritability of EOAD and late-onset Alzheimer disease (AD) using concordance for AD among parent-offspring pairs. SETTING: The Uniform Data...

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Identifiers

PMID: 21911656
DOI: 10.1001/archneurol.2011.221
PMCID: PMC3332307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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