A test for adaptive change in DNA sequences controlling transcription.

doi:10.1098/rspb.1995.0137

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Article

A test for adaptive change in DNA sequences controlling transcription.

Proceedings. Biological sciences - 22 Aug 1995

Jenkins D L, Ortori C A, Brookfield J F

Abstract excerpt

Spatial and temporal differences in gene expression in early development result from the interaction of transcription factors with enhancer and silencer sequences in DNA. The evolution of the developmental process thus involves changes in the DNA sequences that bind transcription factors. Here we advocate a non-parametric statistical test-comparing levels of polymorphism and fixed substitutions between species...

Topics

Animals
Base Sequence
Biological Evolution
Biometry
DNA
DNA Primers
Drosophila
Drosophila melanogaster
Enhancer Elements, Genetic
Gene Expression Regulation, Developmental
Genes, Insect

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Variation

Molecular Sequence Data

Polymorphism, Genetic

Protein Binding

Species Specificity

Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 7568273
DOI: 10.1098/rspb.1995.0137

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7568273-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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