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Article

Molecular population genetic analysis of the streptokinase gene of Streptococcus pyogenes: mosaic alleles generated by recombination.

Molecular microbiology - 1 May 1995

Kapur V, Kanjilal S, Hamrick M R, Li L L, Whittam T S, Sawyer S A, Musser J M

Abstract excerpt

To understand the mechanisms governing molecular evolution of the streptokinase gene (skn), a 384 bp DNA fragment encoding two variable regions of the molecule was characterized in 47 isolates of Streptococcus pyogenes. The results reveal that alleles of the streptokinase gene have a mosaic structure, and provide strong evidence for intragenic recombination. Moreover, organisms that are well differentiated in...

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PMID: 7565111
DOI: 10.1111/j.1365-2958.1995.tb02415.x

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